Corticosteroids in acute traumatic brain injury

Corticosteroids for acute traumatic brain injury.

BACKGROUND Traumatic brain injury is a leading cause of death and disability. Corticosteroids have been widely used in treating people with traumatic brain injury. OBJECTIVES To quantify the effectiveness and safety of corticosteroids in the treatment of acute traumatic brain injury. SEARCH STRATEGY Electronic sources: MEDLINE, EMBASE, Cochrane Library and specialised database searches. Add...

P22: Traumatic Brain Injury

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W7: In Vitro Traumatic Brain Injury Models

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P108: Microglia in Traumatic Brain Injury

Microglia is one of the first innate immune components. These cells account about 5 to 10% of the entire adult brain cells and are activated by trauma. Complex-mediated inflammatory responses occur through cellular and molecular events during and after the traumatic brain injury (TBI). In-lesion area astrocytes, microglia, and damaged neurons begin to secrete cytokines and chemokines. Microglia...

Traumatic Brain Injury – Acute Care